Description

2-Hydroxy-3,3-Dimethylbutyronitrile is a versatile organic nitrile intermediate characterized by its hydroxyl and nitrile functional groups. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring fine chemical synthesis, such as active pharmaceutical ingredient (API) manufacturers and specialty chemical producers, need this high-purity intermediate for its reliable reactivity and structural utility.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its nitrile group for further chemical transformations.
• Fine Chemical Building Block: Employed in organic synthesis for constructing complex molecular architectures found in dyes, pigments, and specialty polymers.
• Chiral Auxiliary/Resolving Agent Precursor: The hydroxyl group adjacent to a tertiary carbon center makes it a candidate for developing chiral reagents used in asymmetric synthesis.
• Research & Development: Utilized in academic and industrial R&D laboratories for method development and exploring novel synthetic pathways.

Basic Information

Product Name	2-Hydroxy-3,3-Dimethylbutyronitrile
CAS No.	33350-17-3
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	2-Hydroxy-3,3-dimethylbutanenitrile; 3,3-Dimethyl-2-hydroxybutyronitrile; Pinacolone cyanohydrin; 2-Cyano-3,3-dimethyl-2-butanol; α-Hydroxypivalonitrile; 3,3-Dimethyl-2-hydroxybutanenitrile; 2-Hydroxy-3,3-dimethylbutyric acid nitrile
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3,3-Dimethylbutyronitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.