Description

[(20S)-5α-Pregnane-3β,16α,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane) CAS NO 33287-36-4 is a high-purity, protected steroid derivative used as a critical synthetic intermediate in advanced pharmaceutical research and development. Its value lies in providing a stable, reactive scaffold for the controlled synthesis of complex steroid-based molecules and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key protected precursor in the multi-step synthesis of complex steroid hormones and their analogs.
• Drug Discovery Research: Used in medicinal chemistry for the design and development of new therapeutic agents targeting hormone receptors.
• Process Chemistry: Serves as a standardized building block for the scale-up and optimization of API manufacturing processes under GMP conditions.
• Biochemical Research: Employed in the study of steroid biosynthesis pathways and enzyme mechanisms as a stable substrate or inhibitor analog.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling.
• Fine Chemical Synthesis: Acts as a versatile intermediate for creating specialized steroid derivatives for various research applications.

Basic Information

Product Name	[(20S)-5α-Pregnane-3β,16α,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane)
CAS No.	33287-36-4
Molecular Formula	C30H60O3Si3
Molecular Weight	553.06 g/mol
Synonyms	5α-Pregnane-3β,16α,20-triol, tris(trimethylsilyl) ether; (20S)-5α-Pregnane-3β,16α,20-triyl tris(trimethylsilyl) ether; 3β,16α,20-Tris(trimethylsiloxy)-5α-pregnane; Pregnane-3β,16α,20-triol TMS ether; Steroid TMS ether intermediate; Tris-O-trimethylsilyl protected pregnane triol
EINECS	Contact for details

Quality Control

Our production of [(20S)-5α-Pregnane-3β,16α,20-Triyl]Tri(Oxy)]Tris(Trimethylsilane) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.