Description

3Beta,4Alpha,17Beta-Tris(Trimethylsiloxy)Androst-5-Ene is a high-purity, steroidal intermediate featuring a fully protected tri-silylated structure, which is critical for advanced synthetic pathways. This compound is valued for its role as a versatile building block in the synthesis of complex pharmaceutical and fine chemical targets, offering enhanced stability and reactivity control. It is primarily sought by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced material sectors for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key protected precursor in the multi-step synthesis of steroid-based active pharmaceutical ingredients (APIs) and hormone analogs.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic routes to complex steroidal molecules and studying structure-activity relationships.
• Fine Chemical Synthesis: Serves as a crucial building block for creating high-value specialty chemicals, including chiral catalysts and advanced material precursors.
• Process Chemistry: Employed in process development and scale-up for manufacturing steroidal compounds under controlled conditions.

Basic Information

Product Name	3Beta,4Alpha,17Beta-Tris(Trimethylsiloxy)Androst-5-Ene
CAS No.	33287-28-4
Molecular Formula	C30H58O3Si3
Molecular Weight	551.03 g/mol
Synonyms	Androst-5-ene-3β,4α,17β-triol, tris(trimethylsilyl) ether; 3β,4α,17β-Tris(trimethylsiloxy)-5-androstene; Tris(trimethylsilyl) ether of Androst-5-ene-3β,4α,17β-triol; 5-Androstene-3β,4α,17β-triol, tris-O-(trimethylsilyl); TMS-protected Androst-5-ene-3β,4α,17β-triol
EINECS	Contact for details

Quality Control

Our 3Beta,4Alpha,17Beta-Tris(Trimethylsiloxy)Androst-5-Ene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.