Description

4-(Bromomethyl)-2-Oxetanone is a versatile and reactive brominated lactone building block, essential for advanced organic synthesis. Its value lies in its bifunctional nature, featuring both a reactive bromomethyl group and a strained β-lactone ring, enabling precise molecular construction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing β-lactam antibiotics, protease inhibitors, and other bioactive molecules with complex ring systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific lactone motifs.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating functional polymers with tailored degradation profiles or reactive side chains.
• Material Science Research: Employed in developing novel coatings, adhesives, and specialty materials that benefit from its ring-opening polymerization potential.
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules due to the electrophilic reactivity of the β-lactone and the handle provided by the bromomethyl group.
• Organic Synthesis Reagent: Acts as a versatile electrophile for alkylation reactions and a precursor for generating other functionalized heterocycles.

Basic Information

Item	Detail
Product Name	4-(Bromomethyl)-2-Oxetanone
CAS No.	33282-42-7
Molecular Formula	C4H5BrO2
Molecular Weight	164.99 g/mol
Synonyms	3-Bromomethyl-β-propiolactone; β-Propiolactone, 3-(bromomethyl)-; 3-(Bromomethyl)oxetan-2-one; Bromomethyl β-propiolactone; 4-Bromomethyl-2-oxetanone; 2-Oxetanone, 4-(bromomethyl)-; (3-Bromomethyl)oxetan-2-one
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-2-Oxetanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up processes. We provide comprehensive analytical data, including HPLC, NMR, and GC-MS profiles. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.