Description

1-[(Trifluoromethyl)Dithio]-n-[(Trifluoromethyl)Thio]Formimidic Acid Fluoride is a specialized organofluorine and organosulfur compound characterized by its unique trifluoromethylthio and dithioformimidic acid fluoride functional groups. This high-value intermediate is critical for introducing the potent SCF3 moiety into target molecules, significantly altering their physicochemical properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients requiring enhanced metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing the trifluoromethylthioether (SCF3) group, a privileged motif in drug discovery for its strong electron-withdrawing and lipophilic properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the SCF3 group improves compound activity, rainfastness, and environmental persistence.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials with tailored surface properties and chemical resistance.
• Fluorination Reagent: Acts as a versatile reagent in organic synthesis for the direct introduction of fluorine-containing groups under controlled conditions.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.

Basic Information

Product Name	1-[(Trifluoromethyl)Dithio]-n-[(Trifluoromethyl)Thio]Formimidic Acid Fluoride
CAS No.	33278-63-6
Molecular Formula	C3F7NS3
Molecular Weight	271.22 g/mol
Synonyms	Formimidic acid, 1-[(trifluoromethyl)dithio]-N-[(trifluoromethyl)thio]-, fluoride; N-[(Trifluoromethyl)thio]-1-[(trifluoromethyl)dithio]formimidic acid fluoride; Trifluoromethylthio-dithioformimidic acid fluoride; SCF3-containing formimidic acid fluoride; Fluoride of N-(trifluoromethylthio)-1-(trifluoromethyldithio)formimidic acid
EINECS	Contact for details

Quality Control

Our production of 1-[(Trifluoromethyl)Dithio]-n-[(Trifluoromethyl)Thio]Formimidic Acid Fluoride adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 19F), HPLC, and GC analysis, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the precise specifications and results. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to minimize volatility and degradation. Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.