Description

1-[(Trifluoromethyl)Dithio]-n-[(Trifluoromethyl)Thio]Formimidic Acid Chloride is a specialized organosulfur and organofluorine compound characterized by its reactive formimidic acid chloride core flanked by trifluoromethylthio and trifluoromethyldithio groups. This unique structure makes it a valuable highly functionalized building block for introducing sulfur and fluorine motifs into target molecules, which are critical for modulating properties like lipophilicity, metabolic stability, and bioactivity. It is primarily sought by pharmaceutical researchers and agrochemical developers engaged in the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing sulfur- and fluorine-containing heterocycles and bioactive molecules in drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides where the trifluoromethylthio group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced materials with unique surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the electron-withdrawing nature of the substituents.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research focused on introducing the SCF3 and S2CF3 groups, which are prized in medicinal and agrochemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex molecules at various scales.

Basic Information

Product Name	1-[(Trifluoromethyl)Dithio]-n-[(Trifluoromethyl)Thio]Formimidic Acid Chloride
CAS No.	33278-62-5
Molecular Formula	C3HF6ClNS3
Molecular Weight	279.68 g/mol
Synonyms	Formimidic chloride, 1-[(trifluoromethyl)dithio]-N-[(trifluoromethyl)thio]-; N-[(Trifluoromethyl)thio]-C-[(trifluoromethyl)dithio]formimidoyl chloride; (Trifluoromethyldithio)(trifluoromethylthio)formimidic chloride; Thiocarbonyl S-((trifluoromethyl)thio) O-((trifluoromethyl)dithio)imidate; TFDTC; A reagent for introducing SCF3 and S2CF3 groups.
EINECS	Contact for details

Quality Control

Our production of 1-[(Trifluoromethyl)Dithio]-n-[(Trifluoromethyl)Thio]Formimidic Acid Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot undergoes comprehensive analysis including HPLC purity and NMR identification. A detailed Certificate of Analysis (COA) providing full specifications is supplied with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its reactivity as a strong acid/organic solvent, keep away from incompatible materials such as bases, oxidizing agents, and moisture. Handle and store under an inert atmosphere for maximum stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.