Description

(2S)-2-Methyl-1,2-Butanediol CAS NO 33204-46-5 is a high-purity, chiral diol characterized by its specific stereochemistry at the 2-position. This compound matters as a valuable chiral building block and intermediate in the synthesis of complex molecules, where its defined stereochemistry is critical for imparting desired biological or material properties. It is needed by research and development laboratories in the pharmaceutical and agrochemical sectors, as well as by manufacturers of specialty chemicals, liquid crystals, and advanced polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of enantiomerically pure drugs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where stereochemistry affects biological activity and environmental safety.
• Liquid Crystal Materials: Serves as a precursor or a core component in the manufacture of chiral liquid crystals for display technologies.
• Polymer Modification: Acts as a monomer or chain extender in the synthesis of specialized polyesters and polyurethanes, influencing polymer flexibility and degradation profiles.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic systems to induce stereoselectivity in chemical reactions.
• Solvent for Specialty Applications: Utilized as a high-boiling, chiral solvent in sensitive chemical processes where its properties are advantageous.

Basic Information

Product Name	(2S)-2-Methyl-1,2-Butanediol
CAS No.	33204-46-5
Molecular Formula	C5H12O2
Molecular Weight	104.15 g/mol
Synonyms	(S)-2-Methyl-1,2-butanediol; (2S)-2-Methylbutane-1,2-diol; L-2-Methyl-1,2-butanediol; (S)-(-)-2-Methyl-1,2-butanediol; 1,2-Butanediol, 2-methyl-, (2S)-; 2-Methyl-1,2-butanediol (S enantiomer); (S)-2-Methyl-1,2-dihydroxybutane
EINECS	Contact for details

Quality Control

Our (2S)-2-Methyl-1,2-Butanediol is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC, GC, and NMR, to verify identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.440 - 1.445
Specific Rotation ([α]20/D)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.