Description

(E)-4-(4-Chlorophenyl)-2-Oxo-But-3-Enoic Acid is a high-purity, light-sensitive organic intermediate characterized by its α,β-unsaturated ketone structure. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging the chlorophenyl moiety for biological activity.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and advanced materials where the conjugated system is essential for optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic synthesis, including cross-coupling and cyclization reactions.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme mechanisms and protein interactions due to its reactive ketone functionality.

Basic Information

Product Name	(E)-4-(4-Chlorophenyl)-2-Oxo-But-3-Enoic Acid
CAS No.	33185-97-6
Molecular Formula	C10H7ClO3
Molecular Weight	210.61 g/mol
Synonyms	(E)-4-(4-Chlorophenyl)-2-oxobut-3-enoic acid; 4-(4-Chlorophenyl)-2-oxo-3-butenoic acid; 3-Butenoic acid, 4-(4-chlorophenyl)-2-oxo-, (E)-; 2-Oxo-4-(p-chlorophenyl)-3-butenoic acid; p-Chlorocinnamoylformic acid; (E)-p-Chlorobenzalpyruvic acid; 33185-97-6; 4-(4-Chlorophenyl)-2-oxobut-3-enoic acid
EINECS	Contact for details

Quality Control

Our (E)-4-(4-Chlorophenyl)-2-Oxo-But-3-Enoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.