Description

Ethanone, 2,2-Difluoro-2-Nitro-1-Phenyl- (9Ci) is a specialized fluorinated and nitrated aromatic ketone building block, identified by CAS NO 33128-13-1. This compound is valued for its unique molecular scaffold, which combines electron-withdrawing groups to enable precise reactivity in advanced synthetic pathways. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the difluoronitroacetophenone structure can contribute to unique biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecules via reactions such as nucleophilic substitution or as a precursor to heterocycles.
• Fluorine Chemistry Studies: A valuable compound for investigating the effects of gem-difluoro and nitro groups on adjacent carbonyl chemistry and aromatic systems.

Basic Information

Product Name	Ethanone, 2,2-Difluoro-2-Nitro-1-Phenyl- (9Ci)
CAS No.	33128-13-1
Molecular Formula	C8H5F2NO3
Molecular Weight	201.13 g/mol
Synonyms	2,2-Difluoro-2-nitro-1-phenylethanone; α,α-Difluoro-α-nitroacetophenone; 1-Phenyl-2,2-difluoro-2-nitroethanone; Difluoronitroacetophenone; NSC 403796; 2-Nitro-2,2-difluoroacetophenone; Phenyldifluoronitroethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2-Difluoro-2-Nitro-1-Phenyl- (9Ci) is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.