Description

2-Butanone, 1,1-Difluoro-1-Nitro- is a specialized fluorinated nitro compound, serving as a versatile building block in advanced organic synthesis. Its unique structure, featuring both fluorine and nitro functional groups, makes it a valuable precursor for introducing fluorinated motifs into target molecules, which is critical for modifying physical and biological properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in medicinal chemistry programs targeting improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or modifier in the development of specialty polymers and advanced materials with specific surface or optical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for various fluorination and nitro-aldol type reactions to create complex molecular architectures.
• Liquid Crystal & Electronic Chemicals: Potential intermediate in the synthesis of fluorinated components for liquid crystal displays (LCDs) and other electronic applications.

Basic Information

Product Name	2-Butanone, 1,1-Difluoro-1-Nitro-
CAS No.	33128-11-9
Molecular Formula	C4H5F2NO2
Molecular Weight	137.09 g/mol
Synonyms	1,1-Difluoro-1-nitrobutan-2-one; 1-Nitro-1,1-difluorobutan-2-one; 2-Butanone, 1,1-difluoro-1-nitro-; 1,1-Difluoro-1-nitro-2-butanone; DFNB
EINECS	Contact for details

Quality Control

Our 2-Butanone, 1,1-Difluoro-1-Nitro- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. For custom synthesis projects or specific purity requirements, our technical team is available to discuss tailored quality specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.