Description

2-Propanone, 1,1-Difluoro-1-Nitro- (8Ci,9Ci) is a specialized fluorinated nitro compound with the CAS number 33128-08-4. This high-value intermediate is prized for its unique reactivity profile, enabling the synthesis of complex molecules in advanced chemical manufacturing. It is primarily sought after by research and development laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoronitroacetone moiety can contribute to improved efficacy and environmental profile.
• Fluorinated Material Precursor: Serves as a starting material for creating specialty polymers, liquid crystals, and electronic chemicals that benefit from fluorine's unique properties.
• Organic Synthesis Reagent: Employed in research-scale organic chemistry for introducing the 1,1-difluoro-1-nitroacetone functional group into target molecules via various condensation or addition reactions.
• Energetic Materials Research: Investigated in controlled R&D settings for potential applications in the formulation of specialized energetic compounds due to its nitro and fluorine content.

Basic Information

Product Name	2-Propanone, 1,1-Difluoro-1-Nitro- (8Ci,9Ci)
CAS No.	33128-08-4
Molecular Formula	C₃H₃F₂NO₃
Molecular Weight	139.06 g/mol
Synonyms	1,1-Difluoro-1-nitroacetone; Difluoronitroacetone; 1-Nitro-1,1-difluoroacetone; 1,1-Difluoro-1-nitropropan-2-one; 2-Propanone, 1,1-difluoro-1-nitro-; NSC 403058; α,α-Difluoro-α-nitroacetone
EINECS	Contact for details

Quality Control

Every batch of 2-Propanone, 1,1-Difluoro-1-Nitro- is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical R&D and scale-up processes. Our quality systems are designed to support applications requiring high-purity intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place away from incompatible materials. Due to its light-sensitive and easily oxidized nature (store under inert atmosphere), it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C). Keep container tightly sealed when not in use to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.