Description

1,4,5,5,6,6-Hexafluoro-2,3-Dimethoxy-1,3-Cyclohexadiene CAS NO 33103-52-5 is a specialized fluorinated organic compound characterized by its unique diene and dimethoxy functional groups. This high-value intermediate is critical for advanced synthesis, particularly in the development of novel materials and active pharmaceutical ingredients where the introduction of fluorine atoms is required to modulate properties. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of fluorinated drug candidates, leveraging fluorine's ability to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, where fluorination improves efficacy and environmental persistence.
• Advanced Material Precursor: Acts as a monomer or precursor for fluorinated polymers, liquid crystals, and specialty coatings with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for studying Diels-Alder reactions and developing new fluorination methodologies.
• Electronics Industry: Investigated for use in the synthesis of fluorinated compounds for dielectric fluids, etchants, or precursors for chemical vapor deposition (CVD).

Basic Information

Product Name	1,4,5,5,6,6-Hexafluoro-2,3-Dimethoxy-1,3-Cyclohexadiene
CAS No.	33103-52-5
Molecular Formula	C8H6F6O2
Molecular Weight	248.12 g/mol
Synonyms	1,3-Cyclohexadiene, 1,4,5,5,6,6-hexafluoro-2,3-dimethoxy-; Hexafluorodimethoxycyclohexadiene; 2,3-Dimethoxy-1,4,5,5,6,6-hexafluoro-1,3-cyclohexadiene; 1,4,5,5,6,6-Hexafluoro-2,3-dimethoxycyclohexa-1,3-diene
EINECS	Contact for details

Quality Control

Our 1,4,5,5,6,6-Hexafluoro-2,3-Dimethoxy-1,3-Cyclohexadiene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO 9001 compliant production for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali. Keep away from incompatible materials and moisture. For long-term storage, consider inert atmosphere conditions to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.