Description

α-(4-Nitrophenylthio)Acetophenone CAS NO 33046-48-9 is a specialized organic sulfur compound featuring a nitrophenylthio moiety attached to an acetophenone core, serving as a critical synthetic intermediate. Its value lies in its unique molecular architecture, which enables the construction of complex molecules in advanced chemical synthesis. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring a nitrophenylthio functional group.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its structure can contribute to biological activity.
• Organic Synthesis Reagent: Acts as a versatile electrophile or coupling partner in cross-coupling reactions and nucleophilic substitution reactions.
• Material Science Precursor: Potential starting material for the synthesis of functionalized polymers or ligands for metal-organic frameworks (MOFs).
• Chemical Biology Probe: Can be utilized in biochemical research to modify proteins or study enzyme mechanisms due to its reactive thioether linkage.

Basic Information

Product Name	α-(4-Nitrophenylthio)Acetophenone
CAS No.	33046-48-9
Molecular Formula	C14H11NO3S
Molecular Weight	273.31 g/mol
Synonyms	2-(4-Nitrophenylthio)-1-phenylethanone; 1-Phenylethanone, 2-[(4-nitrophenyl)thio]-; α-(p-Nitrophenylthio)acetophenone; 2-[(4-Nitrophenyl)sulfanyl]-1-phenylethanone; (4-Nitrophenylthio)acetophenone; p-Nitrophenylthioacetophenone; 4-Nitrobenzenethiol, 2-oxo-2-phenylethyl ester; NSC 163081
EINECS	Contact for details

Quality Control

Our α-(4-Nitrophenylthio)Acetophenone is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.