Description

Ethyl 1-Acetylcyclopropanecarboxylate is a versatile cyclopropane derivative ester, valued as a key synthetic intermediate in advanced organic chemistry. Its unique strained-ring structure and bifunctional reactivity make it a crucial building block for constructing complex molecular architectures. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane motifs, which are common in drug discovery for their metabolic stability and conformational rigidity.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the cyclopropane ring can impart specific biological activity and environmental persistence profiles.
• Organic Synthesis Building Block: Serves as a versatile reagent for [2+1] cycloadditions, ring-opening reactions, and other transformations to introduce the cyclopropane functional group into target molecules.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex esters and lactones that contribute to specific sensory profiles in high-value applications.

Basic Information

Product Name	Ethyl 1-Acetylcyclopropanecarboxylate
CAS No.	32933-03-2
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	1-Acetylcyclopropanecarboxylic Acid Ethyl Ester; Ethyl 1-Acetyl-1-cyclopropanecarboxylate; Ethyl 1-Acetylcyclopropane-1-carboxylate; 1-Carbethoxy-1-acetylcyclopropane; Cyclopropanecarboxylic acid, 1-acetyl-, ethyl ester; 32933-03-2
EINECS	Contact for details

Quality Control

Our Ethyl 1-Acetylcyclopropanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, physical properties, and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is typically stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.460
Density (g/mL at 20°C)	1.05 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.