Description

(3R,5R,6S,7S,9R,11E,13R,14R)-3,5,7,9,13-Pentamethyl-6-Hydroxy-14-Ethyl-1-Oxa-11-Cyclotetradecene-2,4,10-Trione is a high-purity, complex macrolide-derived compound with a defined stereochemistry. It serves as a critical advanced intermediate in the synthesis of specialized pharmaceutical agents and bioactive molecules. This product is essential for research institutions, fine chemical manufacturers, and pharmaceutical R&D departments engaged in developing novel therapeutic compounds, particularly in the antibiotic and anti-inflammatory domains.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex macrolide antibiotics and other active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and metabolic pathway research.
• Organic Synthesis: Serves as a sophisticated starting material for medicinal chemists to create novel chemical entities with potential biological activity.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	(3R,5R,6S,7S,9R,11E,13R,14R)-3,5,7,9,13-Pentamethyl-6-Hydroxy-14-Ethyl-1-Oxa-11-Cyclotetradecene-2,4,10-Trione
CAS No.	32885-75-9
Molecular Formula	C20H30O6
Molecular Weight	366.45 g/mol
Synonyms	3,5,7,9,13-Pentamethyl-6-hydroxy-14-ethyl-1-oxa-11-cyclotetradecene-2,4,10-trione; (3R,5R,6S,7S,9R,11E,13R,14R)-form; Macrolide Intermediate 32885-75-9; 1-Oxa-11-cyclotetradecene-2,4,10-trione derivative; 6-Hydroxy-14-ethyl-3,5,7,9,13-pentamethyl-; (11E)-Isomer; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in cGMP and research-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.