Description

Propanoic Acid, 3-Chloro-2-Hydroxy-, Methyl Ester is a specialized organic ester compound that serves as a valuable chiral building block and intermediate in advanced chemical synthesis. Its unique structure, featuring both chloro and hydroxy functional groups, makes it a versatile precursor for pharmaceuticals, agrochemicals, and fine chemicals. This high-purity intermediate is essential for research and development chemists and production facilities in the pharmaceutical and specialty chemical industries seeking to introduce specific stereochemistry and functionality into target molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing β-lactam antibiotics and other therapeutic agents.
• Agrochemical Synthesis: Used as a precursor in the manufacture of herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Fine Chemical Production: Serves as a building block for complex fragrance compounds, flavors, and advanced material precursors.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating novel compound libraries.
• Polymer Modification: Potential use as a monomer or modifying agent for introducing functional groups into specialty polymer chains.

Basic Information

Product Name	Propanoic Acid, 3-Chloro-2-Hydroxy-, Methyl Ester
CAS No.	32777-04-1
Molecular Formula	C₄H₇ClO₃
Molecular Weight	138.55 g/mol
Synonyms	Methyl 3-Chloro-2-hydroxypropanoate; Methyl 3-Chloro-2-hydroxypropionate; 3-Chloro-2-hydroxypropionic Acid Methyl Ester; 2-Hydroxy-3-chloropropionic Acid Methyl Ester; Methyl (R/S)-3-chloro-2-hydroxypropionate; Chlorohydroxypropionic Acid Methyl Ester; Propanoic acid, 3-chloro-2-hydroxy-, methyl ester (IUPAC); (RS)-Methyl 3-chloro-2-hydroxypropanoate
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Production follows current Good Manufacturing Practices (cGMP) where applicable, and each batch is analyzed to ensure high chemical and isomeric purity. Comprehensive testing includes identity confirmation, assay, and control of key impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place. Containers that are opened must be carefully resealed and kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.