Description

(S)-1-Octyn-3-Ol CAS NO 32556-71-1 is a chiral terminal alkyne alcohol, serving as a versatile and high-value chiral building block in advanced organic synthesis. Its unique structure, featuring both an alkyne and a stereogenic center, makes it indispensable for constructing complex molecules with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Chiral Ligand and Catalyst Synthesis: A key precursor for synthesizing chiral phosphines, N-heterocyclic carbenes (NHCs), and other ligands used in asymmetric catalysis.
• Pharmaceutical Intermediates: Employed in the synthesis of chiral drug candidates, particularly for introducing chiral alcohol or alkyne functionalities into target molecules.
• Agrochemical Research: Used to create chiral analogs of bioactive compounds for crop protection and pest management agents.
• Material Science: Acts as a monomer or cross-linker in the development of specialized polymers with tailored optical or mechanical properties.
• Natural Product Synthesis: A valuable synthon for the total synthesis of complex natural products containing chiral alkyne subunits.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes via click chemistry (azide-alkyne cycloaddition) with stereochemical control.

Basic Information

Product Name	(S)-1-Octyn-3-Ol
CAS No.	32556-71-1
Molecular Formula	C₈H₁₄O
Molecular Weight	126.20 g/mol
Synonyms	(S)-1-Octyn-3-ol; (S)-Oct-1-yn-3-ol; (3S)-1-Octyn-3-ol; (S)-(-)-1-Octyn-3-ol; L-1-Octyn-3-ol; (S)-3-Hydroxy-1-octyne; 1-Octyn-3-ol, (S)-; Chiral 1-octyn-3-ol
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure the chemical and chiral purity of our advanced intermediates. Each batch of (S)-1-Octyn-3-Ol is characterized by modern analytical techniques including chiral HPLC, GC, and NMR to verify identity, purity, and enantiomeric excess (e.e.). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% e.e.
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.