Description

(3R,3'R,6'R,13-Cis)-B,E-Carotene-3,3'-Diol is a specific, high-purity stereoisomer of zeaxanthin, a vital xanthophyll carotenoid. This compound matters for its potent antioxidant properties and its role as a critical component in macular pigment, directly supporting eye health and visual function. It is essential for manufacturers in the nutraceutical, pharmaceutical, and functional food industries seeking a premium, bioavailable ingredient for vision support formulations.

Application

• Dietary Supplements & Nutraceuticals: A key active ingredient in capsules, tablets, and softgels formulated for Age-Related Macular Degeneration (AMD) prevention and overall ocular health.
• Functional Foods & Beverages: Fortification of health drinks, nutritional bars, and dairy products to enhance their vision-supporting claims.
• Pharmaceutical Intermediates: Serves as a high-purity starting material or intermediate in the synthesis of specialized ophthalmologic drugs and advanced carotenoid derivatives.
• Cosmeceuticals: Incorporated into skincare formulations for its antioxidant benefits, helping to protect skin from oxidative stress induced by blue light and environmental factors.
• Animal Nutrition: Used in premium feed additives for poultry to enhance egg yolk pigmentation and for aquaculture to improve the coloration and health of farmed fish.
• Research & Development: A critical reference standard and biochemical reagent in academic, clinical, and industrial research focused on carotenoid metabolism, vision science, and antioxidant mechanisms.

Basic Information

Product Name	(3R,3'R,6'R,13-Cis)-B,E-Carotene-3,3'-Diol
CAS No.	32449-88-0
Molecular Formula	C₄₀H₅₆O₂
Molecular Weight	568.87 g/mol
Synonyms	(13Z)-Zeaxanthin; (13-cis)-Zeaxanthin; (3R,3'R,6'R)-β,ε-Carotene-3,3'-diol; meso-Zeaxanthin (specific stereoisomer); all-trans-Zeaxanthin isomer; Lutein isomer; Xanthophyll; Food Orange 8; CI 75135; E161h
EINECS	251-095-7

Quality Control

Our (3R,3'R,6'R,13-Cis)-B,E-Carotene-3,3'-Diol is produced under strict quality management systems. Each batch is analyzed to meet high-purity standards suitable for nutraceutical and research applications. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and isomer-specific profile via HPLC, ensuring traceability and batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C (refrigerated) or at -20°C for long-term storage to minimize oxidation. The container should be kept in a cool, dry, and well-ventilated area away from heat and ignition sources.

Specification

Item	Specification
Appearance	Orange to red-orange crystalline powder
Identification (HPLC/UV)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (Total Carotenoids)
Isomeric Purity (HPLC)	≥ 90.0% (13-cis-Zeaxanthin)
Solvent Residue (GC)	Meets ICH guidelines
Heavy Metals (ICP-MS)	< 10 ppm
Loss on Drying	< 1.0%
Total Plate Count	< 1000 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.