Description

2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Arabinoic Acid δ-Lactone is a key protected sugar derivative and versatile chiral building block used in sophisticated organic synthesis. Its value lies in providing a masked, functionalized carbohydrate scaffold that is stable to a wide range of reaction conditions, enabling the selective construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing nucleoside analogs, bioactive natural products, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of novel nucleoside and nucleotide analogs with antiviral or anticancer activity.
• Chiral Pool Synthesis: Serves as a valuable source of chirality for the asymmetric synthesis of complex natural products and active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry: Used in the preparation of selectively protected sugars and glycosylation donors for oligosaccharide and glycoconjugate synthesis.
• Agrochemical Research: Employed as a building block for creating novel chiral ligands, catalysts, or active ingredients with specific biological activity.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring precise stereochemical control.
• Process Development & Scale-Up: Supports route scouting and optimization from laboratory research to pilot and commercial-scale manufacturing.

Basic Information

Product Name	2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Arabinoic Acid δ-Lactone
CAS No.	32384-58-0
Molecular Formula	C15H34O5Si3
Molecular Weight	402.68 g/mol
Synonyms	D-Arabino-1,4-lactone, 2,3,4-tris-O-(trimethylsilyl)-; 2,3,4-Tris-O-trimethylsilyl-D-arabinono-1,4-lactone; Tris(trimethylsilyl)-D-arabinono-1,4-lactone; D-Arabinono-1,4-lactone 2,3,4-tris(trimethylsilyl) ether; 1,4-D-Arabinonolactone 2,3,4-tris-O-(trimethylsilyl) derivative; Protected D-Arabinono-1,4-lactone; TMS-protected Arabinono Lactone
EINECS	Contact for details

Quality Control

Every batch of 2-O,3-O,4-o-Tris(Trimethylsilyl)-D-Arabinoic Acid δ-Lactone is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.