Description

2-Chloromandelic Acid Methyl Ester is a versatile chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its structural framework, which is pivotal for constructing complex molecules, particularly in the development of optically active compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, where it serves as a key precursor for active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), especially those requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the chlorinated mandelic acid structure imparts specific biological activity.
• Fine Chemical Production: Serves as a building block for specialty chemicals, including liquid crystals, dyes, and performance materials.
• Asymmetric Synthesis: Employed in methodologies for constructing carbon-carbon bonds and introducing chiral centers in complex organic molecules.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic routes and novel compound libraries.
• Catalyst and Ligand Preparation: Can be utilized in the synthesis of chiral catalysts and ligands for enantioselective transformations.

Basic Information

Product Name	2-Chloromandelic Acid Methyl Ester
CAS No.	32345-60-1
Molecular Formula	C9H9ClO3
Molecular Weight	200.62 g/mol
Synonyms	Methyl 2-Chloromandelate; (RS)-2-Chloro-2-phenylglycolic Acid Methyl Ester; α-Chloromandelic Acid Methyl Ester; Methyl α-Chloromandelate; 2-Chloro-2-phenylacetic Acid Methyl Ester; Methyl (2-chloro-2-phenylacetate); Mandelic acid, 2-chloro-, methyl ester; Methyl (RS)-2-chloro-2-phenylglycolate
EINECS	Contact for details

Quality Control

Our 2-Chloromandelic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.