Description

2-Chloro-Mandelic Acid Methyl Ester is a versatile chiral building block and synthetic intermediate of significant importance in fine chemical synthesis. Its value lies in its structural motif, which is integral to constructing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily needed by research institutions and manufacturers engaged in the development of active pharmaceutical ingredients (APIs), specialty chemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides.
• Fine Chemical Production: Serves as a crucial building block for creating complex organic molecules in specialty chemistry.
• Asymmetric Synthesis: Employed in chiral pool synthesis and the development of stereoselective catalysts.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D labs.
• Ligand and Catalyst Preparation: Used in the preparation of specialized ligands for metal-catalyzed reactions.

Basic Information

Product Name	2-Chloro-Mandelic Acid Methyl Ester
CAS No.	32345-59-8
Molecular Formula	C9H9ClO3
Molecular Weight	200.62 g/mol
Synonyms	Methyl 2-Chloromandelate; Methyl (2-Chlorophenyl)(hydroxy)acetate; 2-Chloro-α-hydroxybenzeneacetic acid methyl ester; (2-Chlorophenyl)(hydroxy)acetic acid methyl ester; α-Hydroxy-2-chlorobenzeneacetic acid methyl ester; Methyl (RS)-2-chloromandelate; DL-2-Chloromandelic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloro-Mandelic Acid Methyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Optical Purity (Chiral HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.