Description

16α-Hydroxy-A(1),28-Dinorlupa-2,17,20(29)-Trien-27-Oic Acid γ-Lactone is a high-purity, specialized triterpenoid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical advanced intermediate for the development of novel bioactive molecules, offering a complex, functionalized scaffold. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of steroids, terpenoids, and other complex natural product analogs.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathways for novel therapeutic agents, particularly in steroid and terpenoid-based drug discovery.
• Chemical Reference Standard: Used as a high-purity analytical standard in quality control and method development for laboratories analyzing complex natural products.
• Academic & Industrial Research: Serves as a precursor for studying structure-activity relationships (SAR) and synthesizing novel chemical entities in medicinal chemistry programs.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures due to its reactive functional groups and defined stereochemistry.
• Natural Product Analog Development: Used to create synthetic analogs of lupane-type triterpenoids for evaluating new biological activities.

Basic Information

Product Name	16α-Hydroxy-A(1),28-Dinorlupa-2,17,20(29)-Trien-27-Oic Acid γ-Lactone
CAS No.	32285-15-7
Molecular Formula	C29H40O3
Molecular Weight	436.63 g/mol
Synonyms	16α-Hydroxy-A(1),28-dinorlupa-2,17,20(29)-trien-27-oic acid γ-lactone; 16α-Hydroxy-1,28-dinorlupa-2,17,20(29)-trien-27-oic acid γ-lactone; (4bS,4cS,5aS,6aS,6bS,7R,9aS,10aS,10bS,12aS)-7-Hydroxy-4b,6a,6b,9a,10a,10b,12a-heptamethyl-1,2,3,4,4a,4b,4c,5,5a,6,6a,6b,7,8,9,9a,10,10a,10b,11,12,12a-docosahydropicen-13-one; Lup-2,17,20(29)-trien-27-oic acid, 16α-hydroxy-1,28-dinor-, γ-lactone; A-Nor-B-homo-16α-hydroxy-28-norlupan-27-oic acid γ-lactone
EINECS	Contact for details

Quality Control

Our 16α-Hydroxy-A(1),28-Dinorlupa-2,17,20(29)-Trien-27-Oic Acid γ-Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP principles for the manufacture of advanced pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.