Description

[(20S)-5β-Pregnane-3α,11β,17,20,21-Pentyl]Penta(Oxy)]Pentakis(Trimethylsilane) is a high-purity, fully protected steroid derivative used as a critical synthetic intermediate. This compound is essential for researchers and manufacturers requiring precise chemical modifications to the pregnane skeleton, a core structure in many bioactive molecules. It is primarily utilized in advanced pharmaceutical research and development, particularly in the synthesis of novel steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid hormones and their analogs.
• Research Chemical: Used in academic and industrial R&D laboratories for studying steroid metabolism and receptor interactions.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in steroid analysis.
• Process Development: Employed in the scale-up and optimization of synthetic routes for steroid-based active pharmaceutical ingredients (APIs).
• Derivatization Agent: The trimethylsilyl (TMS) protecting groups make this compound valuable for gas chromatography (GC) and mass spectrometry (MS) analysis of related steroids.

Basic Information

Item	Details
Product Name	[(20S)-5β-Pregnane-3α,11β,17,20,21-Pentyl]Penta(Oxy)]Pentakis(Trimethylsilane)
CAS No.	32213-62-0
Molecular Formula	C38H78O5Si5
Molecular Weight	759.5 g/mol
Synonyms	5β-Pregnane-3α,11β,17,20,21-pentol, pentakis(O-trimethylsilyl) ether, (20S)-; Penta-TMS ether of 5β-Pregnane-3α,11β,17,20,21-pentol; 3α,11β,17,20,21-Pentakis(trimethylsiloxy)-5β-pregnane; Fully protected 5β-pregnane pentol; Steroid TMS derivative; 32213-62-0; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [(20S)-5β-Pregnane-3α,11β,17,20,21-Pentyl]Penta(Oxy)]Pentakis(Trimethylsilane) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting research and development standards. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.