Description

(1R,4Aα)-Decahydro-5β-Carboxy-3β-Hydroxy-5,8Aβ-Dimethyl-2-Methylene-1-Naphthaleneacetic Acid is a high-purity, functionalized decalin derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and sophisticated chiral building block for the construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical development laboratories for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in steroid-like or terpenoid-based drug discovery programs.
• Advanced Organic Synthesis: Utilized as a complex, polyfunctional starting material or intermediate for constructing intricate natural product analogs and other specialty organic compounds.
• Asymmetric Catalysis Research: Employed in the development and testing of new chiral ligands or catalysts due to its rigid, multi-functional structure.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or advanced materials requiring specific molecular geometry and functionality.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical and chemical analysis.

Basic Information

Product Name	(1R,4Aα)-Decahydro-5β-Carboxy-3β-Hydroxy-5,8Aβ-Dimethyl-2-Methylene-1-Naphthaleneacetic Acid
CAS No.	32179-19-4
Molecular Formula	C₁₇H₂₄O₅
Molecular Weight	308.37 g/mol
Synonyms	5β-Carboxy-3β-hydroxy-5,8aβ-dimethyl-2-methylenedecahydro-1-naphthaleneacetic acid; (1R,4aS,5S,8aS)-5-Carboxy-5,8a-dimethyl-2-methylenedecahydro-1-naphthaleneacetic acid; 3β-Hydroxy-5β-carboxy-5,8aβ-dimethyldecahydro-2-methylenenaphthalene-1-acetic acid; NSC 338710; A functionalized decalin carboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our (1R,4Aα)-Decahydro-5β-Carboxy-3β-Hydroxy-5,8Aβ-Dimethyl-2-Methylene-1-Naphthaleneacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.