Description

[2R,5R,(-)]-2,5-Diethyltetrahydrofuran is a chiral, non-racemic organic compound belonging to the class of substituted tetrahydrofurans. This specific stereoisomer is valued for its role as a versatile chiral building block and solvent in advanced synthetic chemistry. It is primarily sought after by research and development laboratories and fine chemical manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of enantiomerically pure active ingredients.

Application

• Chiral Intermediate: A key starting material or intermediate in the asymmetric synthesis of complex pharmaceutical molecules and agrochemicals.
• Specialty Solvent: Used as a solvent in stereoselective reactions where its chirality can influence reaction outcomes.
• Ligand Synthesis: Serves as a precursor for the synthesis of chiral ligands used in catalysis, such as for asymmetric hydrogenation.
• Fragrance & Flavor Chemistry: Potential use in the synthesis of specific, high-value flavor and fragrance compounds due to its structural motif.
• Material Science Research: Investigated as a monomer or modifying agent for the development of specialized polymers with unique properties.

Basic Information

Product Name	[2R,5R,(-)]-2,5-Diethyltetrahydrofuran
CAS No.	32101-31-8
Molecular Formula	C8H16O
Molecular Weight	128.21 g/mol
Synonyms	(-)-(2R,5R)-2,5-Diethyltetrahydrofuran; (2R,5R)-2,5-Diethyloxolane; 2,5-Diethyltetrahydrofuran, (2R,5R)-(-)-; L-2,5-Diethyltetrahydrofuran; (R,R)-(-)-2,5-Diethyltetrahydrofuran
EINECS	Contact for details

Quality Control

Our chiral chemicals are produced and handled under strict quality control protocols to ensure batch-to-batch consistency and enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral GC/HPLC, NMR, and optical rotation measurement. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 98.0% ee
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.