Description

(S)-2-Butyltetrahydro-1,3,2-Oxazaborole-4-Carboxylic Acid Methyl Ester is a high-value chiral building block and a key intermediate in asymmetric synthesis. This compound is crucial for the preparation of enantiomerically pure pharmaceuticals and fine chemicals, offering significant advantages in reaction selectivity and product purity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and catalysts.

Application

• Asymmetric Synthesis: As a chiral auxiliary or ligand precursor in boron-mediated stereoselective reactions, including aldol and reduction reactions.
• Pharmaceutical Intermediates: A critical building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in CNS and cardiovascular drug candidates.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Catalyst Preparation: Serves as a precursor for novel organoboron catalysts used in organic transformations.
• Material Science Research: Employed in the development of chiral polymers and liquid crystals with specific optical properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	(S)-2-Butyltetrahydro-1,3,2-Oxazaborole-4-Carboxylic Acid Methyl Ester
CAS No.	31970-40-8
Molecular Formula	C9H17BNO3
Molecular Weight	197.05 g/mol
Synonyms	Methyl (S)-2-Butyl-4,5-dihydro-1,3,2-oxazaborole-4-carboxylate; (S)-2-n-Butyl-4,5-dihydro-1,3,2-oxazaborole-4-carboxylic Acid Methyl Ester; (S)-2-Butyl-4,5-dihydro-1,3,2-oxazaborole-4-carboxylic Acid Methyl Ester; (S)-2-Butyl-4,5-dihydrooxazaborole-4-carboxylic Acid Methyl Ester; (S)-Methyl 2-butyl-4,5-dihydro-1,3,2-oxazaborole-4-carboxylate; (4S)-2-Butyl-4,5-dihydro-1,3,2-oxazaborole-4-carboxylic Acid Methyl Ester; (S)-2-Butyl-4,5-dihydro-1,3,2λ³-oxazaborole-4-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of (S)-2-Butyltetrahydro-1,3,2-Oxazaborole-4-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. All materials undergo comprehensive analytical testing, including chiral HPLC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.