Description

n-Butyl Propiolate is a versatile alkyne ester monomer, CAS NO 31952-24-6, prized for its terminal acetylene functionality and reactive ester group. This compound is a critical building block in advanced organic synthesis, enabling the construction of complex molecular architectures through click chemistry and polymerization reactions. It is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to introduce tailored functional groups into their products.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the preparation of active pharmaceutical ingredients (APIs) and complex heterocycles via cycloaddition reactions.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and plant growth regulators requiring specific alkyne motifs.
• Polymer & Material Science: Acts as a monomer for synthesizing specialty polymers, including conductive polymers, adhesives, and coatings with unique properties.
• Click Chemistry Reagent: A fundamental component in Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition) for bioconjugation and material surface modification.
• Organic Synthesis Building Block: Employed in Sonogashira coupling and other cross-coupling reactions to create carbon-carbon bonds in fine chemical manufacturing.
• Liquid Crystal & OLED Material Precursor: Used in the synthesis of advanced electronic materials and display components.

Basic Information

Product Name	n-Butyl Propiolate
CAS No.	31952-24-6
Molecular Formula	C₇H₁₀O₂
Molecular Weight	126.15 g/mol
Synonyms	Butyl Propiolate; Propiolic Acid Butyl Ester; Butyl 2-Propynoate; 2-Propynoic Acid Butyl Ester; n-Butyl Propynoate; Butyl Acetylene Carboxylate; Butyl Propiolate (n-); Butyl Propiolate, 98%
EINECS	Contact for details

Quality Control

Our n-Butyl Propiolate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing specifications for identity, assay, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is 2-8°C for extended stability. Keep container tightly sealed when not in use to prevent moisture absorption and polymerization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 1.0% total
Refractive Index (20°C)	1.425 - 1.435
Density (20°C)	0.95 - 0.98 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.