Description

2-Bromo-4'-Iodoacetophenone is a versatile and highly functionalized aromatic ketone, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of halogen atoms (bromine and iodine) on the acetophenone core, which enables selective cross-coupling reactions and facilitates the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require precise intermediates for drug discovery and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the iodine and bromine substituents are leveraged for bioactivity.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce complex aryl groups.
• Chemical Research & Development: Serves as a standard reagent in academic and industrial R&D labs for methodological studies in halogen chemistry.
• Ligand Precursor: Can be utilized to synthesize novel chelating ligands for catalysis.

Basic Information

Product Name	2-Bromo-4'-Iodoacetophenone
CAS No.	31827-94-8
Molecular Formula	C8H6BrIO
Molecular Weight	324.94 g/mol
Synonyms	1-(4-Iodophenyl)-2-bromoethanone; 2-Bromo-1-(4-iodophenyl)ethanone; 4'-Iodo-2-bromoacetophenone; p-Iodophenacyl bromide; α-Bromo-4'-iodoacetophenone; 4-Iodophenacyl bromide; Ethanone, 2-bromo-1-(4-iodophenyl)-; Bromo(4-iodophenyl)methanone
EINECS	Contact for details

Quality Control

Our 2-Bromo-4'-Iodoacetophenone is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.