Description

2-Butyl-4-Methyl-1,3,2-Oxazaborolidine is a specialized organoboron compound, specifically a cyclic oxazaborolidine, that serves as a highly effective chiral catalyst and reagent in asymmetric synthesis. Its primary value lies in enabling the production of enantiomerically pure intermediates, which are critical for the development of pharmaceuticals and advanced materials. This chemical is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to optimize stereoselective transformations.

Application

• As a chiral catalyst for the enantioselective reduction of prochiral ketones to secondary alcohols.
• Employed in asymmetric Diels-Alder reactions and other cycloadditions for constructing complex chiral frameworks.
• Utilized in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Acts as a key reagent in the preparation of agrochemicals and specialty fine chemicals.
• Used in academic and industrial research for developing new catalytic methodologies.
• Applied in material science for the synthesis of chiral polymers or ligands.

Basic Information

Product Name	2-Butyl-4-Methyl-1,3,2-Oxazaborolidine
CAS No.	31748-11-5
Molecular Formula	C8H17BNO
Molecular Weight	154.04 g/mol
Synonyms	2-Butyl-4-methyl-1,3,2-oxazaborolidine; 4-Methyl-2-butyl-1,3,2-oxazaborolidine; (S)- or (R)-2-Butyl-4-methyl-1,3,2-oxazaborolidine (chiral forms); Oxazaborolidine catalyst; CBS catalyst derivative; Boron heterocycle; Chiral oxazaborolidine reagent.
EINECS	Contact for details

Quality Control

Our 2-Butyl-4-Methyl-1,3,2-Oxazaborolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for catalytic applications. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, enantiomeric excess (where applicable), and impurity profiles. Our quality system is designed to meet the rigorous standards required for research and process development in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep the container tightly sealed when not in use to prevent degradation from atmospheric moisture and oxygen.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/NMR)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.