Description

3-(4-Fluorophenyl)-5(4H)-Isoxazolone CAS NO 31709-51-0 is a versatile heterocyclic building block characterized by its fused isoxazolone and fluorinated phenyl rings. This compound matters for its role as a key synthetic intermediate in the development of advanced pharmaceuticals and agrochemicals, where its unique structure enables the creation of molecules with targeted biological activity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the isoxazolone moiety.
• Fine Chemical Production: Used in the manufacture of complex specialty chemicals, dyes, and functional materials requiring fluorinated aromatic components.
• Academic & Industrial Research: A valuable reagent for method development, heterocyclic chemistry studies, and exploring structure-activity relationships (SAR) in medicinal chemistry programs.
• Chemical Library Development: Employed in combinatorial chemistry and high-throughput screening for the generation of diverse compound libraries for biological evaluation.

Basic Information

Item	Detail
Product Name	3-(4-Fluorophenyl)-5(4H)-Isoxazolone
CAS No.	31709-51-0
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	5(4H)-Isoxazolone, 3-(4-fluorophenyl)-; 3-(p-Fluorophenyl)-5(4H)-isoxazolone; 4-Fluoro-β,3-dioxobenzeneethanamine, N-hydroxy-; 3-(4-Fluorophenyl)-4,5-dihydro-1,2-oxazol-5-one; 4-Fluorophenylisoxazolone; p-Fluorophenylisoxazolone; 31709-51-0 (CAS)
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-5(4H)-Isoxazolone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting full specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.