Description

Josamycin Propionate is a semi-synthetic macrolide antibiotic derived from josamycin, designed for enhanced stability and bioavailability. This compound is valued for its potent antibacterial activity against a range of Gram-positive and some Gram-negative pathogens. It is primarily utilized in the pharmaceutical industry for the research, development, and formulation of veterinary and human medicinal products targeting respiratory and skin infections.

Application

• Veterinary Pharmaceutical Ingredient: A key active component in medicated feeds and injectable solutions for treating bacterial infections in livestock and companion animals.
• Human Pharmaceutical Intermediate: Used in the synthesis and development of advanced antibiotic formulations for clinical use.
• Antimicrobial Research: Serves as a reference standard and active agent in microbiological and pharmacological research studies.
• API Manufacturing: Employed as a critical building block in the production of Active Pharmaceutical Ingredients (APIs) for macrolide antibiotics.

Basic Information

Product Name	Josamycin Propionate
CAS No.	31674-19-8
Molecular Formula	C45H77NO17
Molecular Weight	904.1 g/mol
Synonyms	Josamycin propanoate; Josamycin propionate ester; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-7-{[(2R,3S,4S,6S)-3,4-dihydroxy-6-methyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-6-{[(2S,3R,4S,6R)-3,4-dihydroxy-6-methyloxan-2-yl]oxy}oxacyclotetradecane-2,10-dione propionate; Propanoic acid, (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-7-{[(2R,3S,4S,6S)-3,4-dihydroxy-6-methyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxo-6-{[(2S,3R,4S,6R)-3,4-dihydroxy-6-methyloxan-2-yl]oxy}oxacyclotetradec-3-yl ester
EINECS	Contact for details

Quality Control

Our Josamycin Propionate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.