Description

Deisovaleryl Josamycin is a semi-synthetic derivative of the macrolide antibiotic josamycin, characterized by its modified ester side chain. This chemical modification is significant for enhancing the compound's pharmacokinetic properties and broadening its spectrum of antibacterial activity. It serves as a crucial pharmaceutical intermediate for the research and development of advanced antibiotic formulations targeting resistant bacterial strains.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of next-generation macrolide antibiotics with improved efficacy.
• Antibacterial Research: Key starting material in medicinal chemistry for developing novel antibacterial agents against Gram-positive and atypical pathogens.
• Veterinary Medicine: Used in the development of antibiotic treatments for livestock and companion animals.
• Microbiological Studies: Employed as a reference standard or active compound in antimicrobial susceptibility testing and mechanism-of-action studies.
• API Synthesis: Intermediate in the multi-step production of Active Pharmaceutical Ingredients (APIs) for finished dosage forms.

Basic Information

Product Name	Deisovaleryl Josamycin
CAS No.	31642-61-2
Molecular Formula	C45H77NO17
Molecular Weight	904.1 g/mol
Synonyms	Deisovaleryljosamycin; 4''-O-Isovaleryljosamycin; Josamycin 4''-isovalerate; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-12,13-dihydroxy-7-{[(2R,3S,4S,6S)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-6-{[(2S,3R,4S,6R)-3,4,6-trihydroxy-4-(3-methylbutanoyl)oxan-2-yl]oxy}oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our Deisovaleryl Josamycin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.