Description

1,1-Bis(Trimethylsilyloxy)-1-Propene is a specialized organosilicon compound featuring a reactive enol silyl ether structure. This unique chemistry makes it a valuable versatile building block and protecting group reagent in advanced organic synthesis. It is primarily sought after by pharmaceutical, agrochemical, and fine chemical R&D and production teams for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing propene-derived moieties under mild conditions.
• Advanced Organic Synthesis: Serves as a protected enolate equivalent in aldol, alkylation, and Michael addition reactions, enabling precise carbon-carbon bond formation.
• Agrochemical Manufacturing: Used in the production of specialized herbicides, fungicides, and plant growth regulators requiring silicon-containing intermediates.
• Material Science Precursor: Acts as a starting material for synthesizing silicon-modified polymers and specialty silicone derivatives.
• Cross-Coupling Reactions: Employed in palladium-catalyzed and other metal-mediated coupling protocols to install functionalized propene units.
• Laboratory Reagent: Utilized in academic and industrial research for method development and exploring new synthetic pathways.

Basic Information

Item	Detail
Product Name	1,1-Bis(Trimethylsilyloxy)-1-Propene
CAS No.	31469-22-4
Molecular Formula	C9H22O2Si2
Molecular Weight	218.44 g/mol
Synonyms	1-Propene, 1,1-bis[(trimethylsilyl)oxy]-; 1,1-Bis-O-(trimethylsilyl)-1-propenol; 1,1-Bis(trimethylsiloxy)propene; 1,1-Di-O-trimethylsilyl-1-propenol; Enol Bis(trimethylsilyl) Ether of Pyruvic Aldehyde; (1,1-Bis(trimethylsilyloxy)propene); TMS enol ether of methylglyoxal
EINECS	Contact for details

Quality Control

Our 1,1-Bis(Trimethylsilyloxy)-1-Propene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.