Description

Cyclobutyl-4-Fluorophenyl Ketone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a cyclobutyl ring and a fluorinated phenyl group, makes it a valuable precursor for creating novel molecular architectures with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenyl moiety.
• Liquid Crystal & OLED Materials: Used in the synthesis of advanced organic electronic materials, where its rigid, fluorinated structure can influence charge transport and luminescent properties.
• Chemical Synthesis Reagent: Acts as a versatile electrophile or coupling partner in cross-coupling reactions, Grignard reactions, and reductions to create more complex ketones or alcohols.
• Academic & Industrial R&D: Employed in methodological studies and as a model compound for investigating new synthetic pathways involving fluorinated aromatics.

Basic Information

Product Name	Cyclobutyl-4-Fluorophenyl Ketone
CAS No.	31431-13-7
Molecular Formula	C₁₁H₁₁FO
Molecular Weight	178.20 g/mol
Synonyms	4-Fluorophenyl Cyclobutyl Ketone; 1-(4-Fluorophenyl)-1-cyclobutylethanone; 4'-Fluorocyclobutyl Phenyl Ketone; Cyclobutyl(4-fluorophenyl)methanone; (4-Fluorophenyl)(cyclobutyl)ketone; 4-Fluorobenzoylcyclobutane; p-Fluorocyclobutylphenyl Ketone
EINECS	Contact for details

Quality Control

Our Cyclobutyl-4-Fluorophenyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.