Description

1-(1,1,2,2,3,3,3-Heptafluoropropyl)-4-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane is a high-purity, specialty fluorinated bicyclic orthoester compound. This advanced chemical intermediate is valued for its unique molecular architecture, which combines a robust bicyclic cage structure with a highly fluorinated side chain, imparting exceptional stability and reactivity in demanding synthetic environments. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated, sterically hindered motifs that can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorinated orthoester group can contribute to improved efficacy and environmental profile.
• Advanced Material Precursor: Acts as a monomer or cross-linking agent in the production of specialty polymers, coatings, and resins designed for high thermal stability, chemical resistance, and low surface energy.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to create novel ligand systems that leverage the electron-withdrawing and steric properties of the fluorinated cage structure.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research focused on exploring new fluorination methodologies and the properties of heavily fluorinated organic molecules.

Basic Information

Product Name	1-(1,1,2,2,3,3,3-Heptafluoropropyl)-4-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane
CAS No.	31185-67-8
Molecular Formula	C10H9F7O3
Molecular Weight	310.17 g/mol
Synonyms	4-Methyl-1-(heptafluoropropyl)-2,6,7-trioxabicyclo[2.2.2]octane; Heptafluoropropyl Methyl Trioxabicyclooctane; HFPMTO; 2,6,7-Trioxa-1-azoniabicyclo[2.2.2]octane, 1-(heptafluoropropyl)-4-methyl-; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-methyl-2,6,7-trioxa-, heptafluoropropyl ester (related structure); Fluorinated bicyclic orthoester
EINECS	Contact for details

Quality Control

Our production of 1-(1,1,2,2,3,3,3-Heptafluoropropyl)-4-Methyl-2,6,7-Trioxabicyclo[2.2.2]Octane adheres to a strict quality management system. Every batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific research or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.