Description

5-Iodopicolinaldehyde is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic combination of an aldehyde functional group and an iodine atom on the pyridine ring, enabling it to serve as a key precursor for complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active ingredients and functional ligands.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactivity to create complex bioactive molecules.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other conjugated systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.

Basic Information

Product Name	5-Iodopicolinaldehyde
CAS No.	31181-91-6
Molecular Formula	C6H4INO
Molecular Weight	233.01 g/mol
Synonyms	5-Iodopyridine-2-carboxaldehyde; 2-Pyridinecarboxaldehyde, 5-iodo-; 5-Iodo-2-formylpyridine; 5-Iodopicolinaldehyde; 5-Iodo-2-pyridinecarboxaldehyde; Picolinaldehyde, 5-iodo-; 5-Iodopyridine-2-aldehyde
EINECS	Contact for details

Quality Control

Our 5-Iodopicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.