Description

5-Chloro-2-Formylpyridine is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a chloro and a formyl substituent, makes it an essential precursor for constructing complex heterocyclic systems and functional molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS) and as kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and functional polymers.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D labs.

Basic Information

Product Name	5-Chloro-2-Formylpyridine
CAS No.	31181-89-2
Molecular Formula	C6H4ClNO
Molecular Weight	141.55 g/mol
Synonyms	5-Chloropyridine-2-carboxaldehyde; 2-Formyl-5-chloropyridine; 5-Chloro-2-pyridinecarboxaldehyde; 5-Chloropicolinaldehyde; 2-Pyridinecarboxaldehyde, 5-chloro-; 5-Chloro-2-aldehydopyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for 5-Chloro-2-Formylpyridine to ensure batch-to-batch consistency and high purity. Our standard grade typically meets a purity specification of ≥98% (by HPLC), suitable for research and industrial synthesis. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We can provide material tailored to specific project requirements, including higher purity grades for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.