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2-Deoxy-2-Fluoro-D-Mannose CAS NO 31077-88-0
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CAS No.:31077-88-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Deoxy-2-Fluoro-D-Mannose is a fluorinated monosaccharide derivative of significant interest in pharmaceutical research and development. This compound serves as a crucial synthetic intermediate and a key building block for the creation of novel diagnostic and therapeutic agents. It is primarily utilized by researchers and manufacturers in the radiopharmaceutical, oncology, and molecular imaging sectors for the development of advanced PET (Positron Emission Tomography) tracers and targeted therapies.
Application
- Radiopharmaceutical Precursor: A critical intermediate in the synthesis of Fluorodeoxyglucose (FDG) analogs and other fluorine-18 labeled PET imaging agents for cancer diagnostics.
- Oncology Research: Used in the development of glycomimetic drugs and targeted cancer therapeutics that exploit altered glucose metabolism in tumor cells.
- Molecular Probe Synthesis: Serves as a building block for creating fluorescent or isotopically labeled probes to study carbohydrate metabolism and glycosylation processes.
- Glycobiology Studies: Employed in enzymatic and metabolic pathway research to investigate the role of fluorinated sugars in cellular systems.
- Antiviral Agent Development: Explored as a precursor in the synthesis of nucleoside analogs with potential antiviral activity.
- Contrast Agent Formulation: Investigated for use in the formulation of advanced contrast media for medical imaging techniques.
Basic Information
| Product Name | 2-Deoxy-2-Fluoro-D-Mannose |
| CAS No. | 31077-88-0 |
| Molecular Formula | C6H11FO5 |
| Molecular Weight | 182.15 g/mol |
| Synonyms | 2-Fluoro-2-deoxy-D-mannose; 2-Fluoro-D-mannose; 2-Deoxy-2-fluoro-D-mannopyranose; FDMan; 2-FDM; D-2-Fluoromannose; 2-Fluoro-2-deoxy-mannose; 2-Fluoromannose |
| EINECS | Contact for details |
Quality Control
Our 2-Deoxy-2-Fluoro-D-Mannose is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' regulatory and compliance needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Specific Rotation | Contact for details |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Related Substances (HPLC) | Individual impurity ≤ 0.5%; Total impurities ≤ 1.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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