Description

3-Hydroxy-3-Methylvaleric Acid Ethyl Ester is a versatile chiral building block and ester derivative of 3-hydroxy-3-methylvaleric acid. This compound matters for its role as a key intermediate in the synthesis of complex pharmaceutical molecules, particularly statins and other active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing specific molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of HMG-CoA reductase inhibitors (statins) and other therapeutic agents.
• Agrochemical Synthesis: Used as a building block for creating advanced pesticides and herbicides with specific stereochemical requirements.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty chemicals where ester functionality is essential.
• Academic & Industrial Research: Employed in methodological development and asymmetric synthesis studies within organic chemistry laboratories.
• Polymer Chemistry: Can act as a monomer or co-monomer for producing specialized polyesters with unique properties.

Basic Information

Product Name	3-Hydroxy-3-Methylvaleric Acid Ethyl Ester
CAS No.	31033-23-5
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	Ethyl 3-Hydroxy-3-methylvalerate; 3-Hydroxy-3-methylpentanoic acid ethyl ester; Ethyl 3-hydroxy-3-methylpentanoate; 3-Methyl-3-hydroxypentanoic acid ethyl ester; HMVE; 3-Hydroxy-3-methylvaleric acid ethyl ester; (RS)-Ethyl 3-hydroxy-3-methylpentanoate; (±)-Ethyl 3-hydroxy-3-methylpentanoate
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-3-Methylvaleric Acid Ethyl Ester is produced under strict quality management systems. The product undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high chemical purity and consistent chiral integrity suitable for advanced synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.