Description

(1Ar,4E,7S,7Ar,8S,10As,10Br)-7-Acetoxy-2,3,6,7,7A,8,10A,10B-Octahydro-1A,5,8-Trimethyloxireno[9,10]Cyclodeca[1,2-B]Furan-9(1Ah)-One is a complex, high-purity sesquiterpene lactone derivative with a unique oxireno-fused cyclodecane structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile chiral building block for sophisticated organic synthesis. It is essential for research and development in the pharmaceutical and agrochemical sectors, particularly for projects requiring stereochemically defined, polycyclic frameworks to probe biological activity or develop novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel therapeutic agents, especially in oncology and anti-inflammatory drug discovery.
• Agrochemical Research: Used as a sophisticated template for developing new pesticides and herbicides with specific modes of action.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and exploring new chemical space.
• Biochemical Probe Development: Serves as a starting material for creating labeled compounds or probes to study enzyme mechanisms and biological pathways.
• Fine Chemical Production: Integral in multi-step synthesis processes for high-value, low-volume specialty chemicals.

Basic Information

Product Name	(1Ar,4E,7S,7Ar,8S,10As,10Br)-7-Acetoxy-2,3,6,7,7A,8,10A,10B-Octahydro-1A,5,8-Trimethyloxireno[9,10]Cyclodeca[1,2-B]Furan-9(1Ah)-One
CAS No.	31025-59-9
Molecular Formula	C20H26O5
Molecular Weight	346.42 g/mol
Synonyms	7-Acetoxy-2,3,6,7,7a,8,10a,10b-octahydro-1a,5,8-trimethyloxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one; Parthenolide 7-acetate derivative; Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one, 7-(acetyloxy)-2,3,6,7,7a,8,10a,10b-octahydro-1a,5,8-trimethyl-, (1aR,4E,7S,7aR,8S,10aS,10bR)-; Sesquiterpene lactone acetate; Germacranolide derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, GC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support development and commercial projects requiring compliance with cGMP and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.