Description

17,21-[(Butylboranediyl)Bis(Oxy)]-5β-Pregnane-3,20-Dione is a high-purity, synthetic steroid derivative characterized by its unique boronate ester functionalization. This compound serves as a critical advanced intermediate in the research and development of novel pharmaceutical agents, particularly in the fields of endocrinology and oncology. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the synthesis of targeted therapeutic molecules and as a reference standard in analytical studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroid-based therapeutics and prodrugs.
• Research Chemical: Used in academic and industrial R&D for studying steroid receptor interactions and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Probe: Utilized in mechanistic studies to investigate enzyme inhibition and hormonal activity.
• Process Development: Employed in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).

Basic Information

Product Name	17,21-[(Butylboranediyl)Bis(Oxy)]-5β-Pregnane-3,20-Dione
CAS No.	31012-68-7
Molecular Formula	C₂₉H₄₅BO₄
Molecular Weight	480.48 g/mol
Synonyms	5β-Pregnane-3,20-dione, 17,21-[(butylboranediyl)bis(oxy)]-; 17,21-O-(Butylboranediyl)-5β-pregnane-3,20-dione; Butylboronic Acid Pregnane Dione Ester; 31012-68-7; Pregnane-3,20-dione boronate ester
EINECS	Contact for details

Quality Control

Our 17,21-[(Butylboranediyl)Bis(Oxy)]-5β-Pregnane-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen in a sealed container. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.