Description

(20R)-17,20-(Methylboranediylbisoxy)-5β-Pregnan-3α-Ol CAS NO 31012-66-5 is a high-purity, synthetic steroid derivative characterized by a unique boronate ester functional group. This compound is a critical advanced pharmaceutical intermediate (API intermediate) for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in steroid chemistry and targeted drug synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of enzyme inhibitors or receptor modulators.
• Steroid Chemistry: Serves as a versatile precursor for further chemical modifications due to its reactive boronate ester moiety.
• Biochemical Research: Potential use as a probe or tool compound in biochemical assays studying steroid hormone pathways.
• Process Development: Employed in scaling up synthetic routes for pilot and commercial-scale manufacturing of target molecules.

Basic Information

Item	Detail
Product Name	(20R)-17,20-(Methylboranediylbisoxy)-5β-Pregnan-3α-Ol
CAS No.	31012-66-5
Molecular Formula	C23H39BO3
Molecular Weight	374.36 g/mol
Synonyms	17,20-(Methylboranediylbisoxy)-5β-pregnan-3α-ol, (20R)-; 5β-Pregnan-3α-ol, 17,20-(methylboranediylbisoxy)-, (20R)-; 3α-Hydroxy-5β-pregnan-17,20-methylboronate; Pregnan-3α-ol boronate derivative; Steroid boronate ester; 31012-66-5; (20R)-17,20-(Methylboranediylbis(oxy))-5β-pregnan-3α-ol
EINECS	Contact for details

Quality Control

Our (20R)-17,20-(Methylboranediylbisoxy)-5β-Pregnan-3α-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and moisture. Keep the container tightly sealed in a dry environment to prevent degradation from hygroscopic absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.