Description

17,21-[(tert-Butylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione is a high-purity, advanced pharmaceutical intermediate characterized by its specific boronate ester functionalization on a pregnane backbone. This compound is critical for the synthesis of complex steroid derivatives and other bioactive molecules, offering researchers and manufacturers a reliable building block for drug discovery and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical producers specializing in steroid chemistry and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel steroid-based therapeutics and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities targeting hormone receptors.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex molecular architectures in advanced organic synthesis.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study enzyme inhibition or receptor binding mechanisms.

Basic Information

Product Name	17,21-[(tert-Butylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione
CAS No.	30888-68-7
Molecular Formula	C29H43BO5
Molecular Weight	482.46 g/mol
Synonyms	5β-Pregnane-3,11,20-trione, 17,21-[(1,1-dimethylethyl)boranediyl]bis[oxy]-; 17,21-O-(tert-Butylboranediyl)-5β-pregnane-3,11,20-trione; tert-Butylboronic Acid 17,21-Ester of 5β-Pregnane-3,11,20-trione; 5β-Pregnane-3,11,20-trione 17,21-(tert-butylboronate)
EINECS	Contact for details

Quality Control

Our production of 17,21-[(tert-Butylboranediyl)Bisoxy]-5β-Pregnane-3,11,20-Trione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.