Description

17,21-[(tert-Butylboranediyl)Bis(Oxy)]-3α-Hydroxy-5β-Pregnan-20-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific steroidal boronate structure. This compound is critical for research and development in synthetic organic chemistry, particularly in the targeted synthesis of novel steroid derivatives and complex bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents and chemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Research & Development: Used as a critical reagent in academic and industrial R&D for exploring new synthetic pathways and structure-activity relationships (SAR).
• Process Chemistry: Serves as a pivotal intermediate in process development and scale-up for the production of specialized steroid compounds.
• Chemical Biology: Employed in the synthesis of chemical probes for studying steroid hormone receptors and related biological pathways.
• Fine Chemical Synthesis: Utilized in the custom synthesis of high-value, complex organic molecules for various industrial applications.

Basic Information

Product Name	17,21-[(tert-Butylboranediyl)Bis(Oxy)]-3α-Hydroxy-5β-Pregnan-20-One
CAS No.	30888-61-0
Molecular Formula	C₂₉H₄₉BO₄
Molecular Weight	472.51 g/mol
Synonyms	3α-Hydroxy-5β-pregnan-20-one 17,21-(tert-butylboranediyl) acetal; 17,21-O-(tert-Butylboranediyl)-3α-hydroxy-5β-pregnan-20-one; 5β-Pregnan-20-one, 17,21-[(1,1-dimethylethyl)boranediyl]bis(oxy)-3α-hydroxy-; Steroid boronate intermediate 30888-61-0; 3α-Hydroxy-5β-pregnan-20-one cyclic 17,21-(tert-butylboronate); Pregnan-20-one boronate derivative
EINECS	Contact for details

Quality Control

Our 17,21-[(tert-Butylboranediyl)Bis(Oxy)]-3α-Hydroxy-5β-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.