Description

3α-Hydroxy-17,21-[(Methylboranediyl)Bisoxy]-5β-Pregnan-20-One is a high-purity, synthetic steroid derivative with a unique boronate ester functionalization. This compound is a critical advanced intermediate for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies specializing in endocrinology, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in enzymatic studies and receptor binding assays related to steroid hormone pathways.
• Process Chemistry: Serves as a pivotal intermediate in multi-step organic synthesis for producing more complex, biologically active molecules.
• Academic Research: Employed in universities and R&D labs for investigating steroid chemistry, reaction mechanisms, and boronate chemistry applications.

Basic Information

Product Name	3α-Hydroxy-17,21-[(Methylboranediyl)Bisoxy]-5β-Pregnan-20-One
CAS No.	30888-60-9
Molecular Formula	C23H37BO4
Molecular Weight	388.35 g/mol
Synonyms	3α-Hydroxy-17,21-[(methylboranediyl)bis(oxy)]-5β-pregnan-20-one; 5β-Pregnan-20-one, 3α-hydroxy-17,21-[(methylboranediyl)bis(oxy)]-; 17,21-O-(Methylboranediyl)-3α-hydroxy-5β-pregnan-20-one; 3α-Hydroxy-17,21-O-(methylboranediyl)-5β-pregnan-20-one; Steroid Boronate Ester; Pregnane Boronate Derivative
EINECS	Contact for details

Quality Control

Our 3α-Hydroxy-17,21-[(Methylboranediyl)Bisoxy]-5β-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets stringent specifications for research use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.