Description

17,21-[(Phenylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione is a high-purity, synthetic steroid derivative characterized by its unique boronate ester functionalization. This compound is a critical advanced pharmaceutical intermediate (API intermediate) used in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers specializing in steroid chemistry and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroid-based pharmaceuticals and prodrugs.
• Research Chemical: Used in academic and industrial research for studying steroid receptor interactions and metabolic pathways.
• Prodrug Development: The boronate ester group serves as a protective moiety or a targeting ligand in advanced prodrug design.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Bioconjugation: Potential use in creating steroid-protein conjugates for diagnostic or therapeutic applications.

Basic Information

Product Name	17,21-[(Phenylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione
CAS No.	30888-59-6
Molecular Formula	C28H35BO4
Molecular Weight	446.39 g/mol
Synonyms	5β-Pregnane-3,20-dione, 17,21-[(phenylboranediyl)bisoxy]-; 17,21-Phenylboranediylidenedioxy-5β-pregnane-3,20-dione; 3,20-Dioxo-5β-pregnane-17,21-diyl Phenylboronate; Phenylboronic Acid Pregnane Dione Ester; 30888-59-6; 5β-Pregnane-3,20-dione 17,21-phenylboronate
EINECS	Contact for details

Quality Control

Our 17,21-[(Phenylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting R&D and cGMP-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.