Description

17,21-[(Cyclohexylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione is a high-purity, synthetic steroid derivative characterized by its unique boronate ester functionalization. This compound serves as a critical advanced pharmaceutical intermediate and a versatile research chemical for the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in steroid chemistry and targeted drug synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel corticosteroid analogs and other bioactive steroid molecules.
• Research & Development: Used in academic and industrial research for studying steroid receptor interactions and metabolic pathways.
• Process Chemistry: Serves as a precursor in multi-step synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology: Probe molecule for investigating enzyme inhibition and developing targeted therapies.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical analysis.
• Custom Synthesis: Starting point for the preparation of specialized boronate-containing steroid derivatives for proprietary research programs.

Basic Information

Item	Details
Product Name	17,21-[(Cyclohexylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione
CAS No.	30888-58-5
Molecular Formula	C₂₈H₄₁BO₄
Molecular Weight	452.44 g/mol
Synonyms	5β-Pregnane-3,20-dione, 17,21-[(cyclohexylboranediyl)bisoxy]-; 17,21-Cyclohexylboranediyldioxy-5β-pregnane-3,20-dione; Cyclohexylboronic acid 17,21-cyclic ester with 5β-pregnane-3,20-dione; 17,21-O-(Cyclohexylboranediyl)-5β-pregnane-3,20-dione; 5β-Pregnane-3,20-dione 17,21-cyclohexylboronate
EINECS	Contact for details

Quality Control

Our 17,21-[(Cyclohexylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and pharmaceutical use. A detailed Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.