Description

17,21-[(tert-Butylboranediyl)Bis(Oxy)]-5β-Pregnane-3,20-Dione is a high-purity, organoboron-modified steroid derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical synthetic intermediate or reference standard for the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology. Pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers specializing in steroid chemistry are the primary users who need this material for its precise chemical functionality.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Research Chemical: Used as a reference standard or probe molecule in biochemical and pharmacological research to study steroid receptor interactions and metabolic pathways.
• Process Development: Employed in the development and optimization of scalable synthetic routes for novel therapeutic compounds within R&D and pilot-scale facilities.
• Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic chemistry, medicinal chemistry, and chemical biology.
• Analytical Standard: Acts as a high-purity standard for quality control (QC) and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical analysis.

Basic Information

Product Name	17,21-[(tert-Butylboranediyl)Bis(Oxy)]-5β-Pregnane-3,20-Dione
CAS No.	30888-57-4
Molecular Formula	C₂₆H₄₁BO₄
Molecular Weight	428.42 g/mol
Synonyms	5β-Pregnane-3,20-dione, 17,21-[(1,1-dimethylethyl)boranediyl]bis[oxy]-; 17,21-O-(tert-Butylboranediyl)-5β-pregnane-3,20-dione; tert-Butylboronic Ester of 5β-Pregnane-3,20-dione-17,21-diol; 30888-57-4; Steroid tert-butylboronate ester
EINECS	Contact for details

Quality Control

Our 17,21-[(tert-Butylboranediyl)Bis(Oxy)]-5β-Pregnane-3,20-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥95% by HPLC), and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.