Description

17,21-[(Methylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione is a specialized steroid derivative, notable for its unique boronate ester functionalization. This compound serves as a critical advanced pharmaceutical intermediate and a valuable research chemical for the development of novel therapeutic agents and diagnostic tools. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in steroid chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroid-based drugs and prodrugs.
• Medicinal Chemistry Research: Used as a precursor for developing boron-containing compounds for Boron Neutron Capture Therapy (BNCT) and other targeted therapies.
• Biochemical Probe: Serves as a tool compound for studying enzyme inhibition, receptor binding, and metabolic pathways involving steroid hormones.
• Reference Standard: Employed in analytical laboratories for method development, quality control, and regulatory compliance testing.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.
• Process Development: Acts as a model compound for scaling up and optimizing complex synthetic routes in fine chemical production.

Basic Information

Product Name	17,21-[(Methylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione
CAS No.	30888-56-3
Molecular Formula	C23H35BO4
Molecular Weight	386.33 g/mol
Synonyms	5β-Pregnane-3,20-dione, 17,21-[(methylboranediyl)bisoxy]-; 17,21-(Methylboranediyl)dioxy-5β-pregnane-3,20-dione; 3,20-Dioxo-5β-pregnane-17,21-diyl methylboronate; Methylboronic acid 17,21-cyclic ester with 5β-pregnane-3,20-dione-17,21-diol
EINECS	Contact for details

Quality Control

Every batch of 17,21-[(Methylboranediyl)Bisoxy]-5β-Pregnane-3,20-Dione is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards, including identity confirmation, purity analysis, and impurity profiling. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.