Description

17,21-[(Phenylboranediyl)Bisoxy]Pregn-4-Ene-3,20-Dione is a high-purity, synthetic steroid derivative characterized by a unique phenylboranediyl bisoxy functional group. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile research chemical for the development of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in steroid chemistry and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel corticosteroid analogs and other steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial research for studying structure-activity relationships (SAR) in steroid-based drug discovery.
• Chemical Synthesis: Serves as a precursor for creating more complex molecules with potential anti-inflammatory, immunosuppressive, or hormonal activity.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and method development for HPLC or LC-MS analysis.
• Biochemical Research: Investigated for its interaction with steroid hormone receptors and related enzymatic pathways.

Basic Information

Product Name	17,21-[(Phenylboranediyl)Bisoxy]Pregn-4-Ene-3,20-Dione
CAS No.	30888-55-2
Molecular Formula	C28H33BO4
Molecular Weight	444.37 g/mol
Synonyms	17,21-[(Phenylboranediyl)bis(oxy)]pregn-4-ene-3,20-dione; 17,21-Phenylboronated Pregnenedione; 3,20-Dioxopregn-4-en-17,21-diyl Phenylboronate; Pregn-4-ene-3,20-dione, 17,21-[(phenylboranediyl)bis(oxy)]-; (17R,21R)-17,21-[(Phenylboranediyl)bis(oxy)]pregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our 17,21-[(Phenylboranediyl)Bisoxy]Pregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting specifications for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.